Patent · US Expired

EPF derived peptides and therapeutic compositions

US7402563B2 · kind B2 · utility

0Cited by

0References

5Claims

0Family size

Assignee

Janssen Pharmaceutica NA · BE

Inventors

Arjan Buist · Beerse, BE
Eckhard Bender · Langenfeld, DE
Tom J. L. Meeusen · Leuven, BE
Elke J. H. Clynen · Leuven, BE
Liliane Schoofs · Kessel-Lo, BE

Key dates

Filing date	Mar 22, 2006
Grant date	Jul 22, 2008
Priority date	—
Expiry date	Mar 22, 2026

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/368
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention provides assays for the study of the interaction of EPF and its EPF-related peptides with a hDRR receptor. The assays are useful to identify whether a test compound can bind to the hDRR receptor under conditions in which EPF or related peptide can bind to the receptor. The assays are also useful to determine whether the test compound is an agonist or antagonist of hDRRs. The above assays can be performed in a variety of formats including competitive, non-competitive and comparative assays in which the interaction of EPF or EPF-related peptides with hDRRs is assessed as a positive or negative control or compared to the results obtained with the test compound.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.