4-amino-substituted pyrimidine derivatives

US7410973B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Achim Feurer · Wilhelmsfeld, DE
• Joachim Luithle · Wülfrath, DE
• Stephan-Nicholas Wirtz · Wuppertal, DE
• Gerhard Konig · Düsseldorf, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Elke Stahl · Bensberg, DE
• Rudy Schreiber · Menlo Park, US
• Frank Wunder · Wuppertal, DE
• Dieter Lang · Velbert, DE

Key dates

• Filing date: Jul 7, 2003
• Grant date: Aug 12, 2008
• Expiry date: Mar 28, 2024

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel 4-amino-substituted pyrimidine derivatives which stimulate soluble guanylate cyclase, to processes for the preparation thereof, and to the use thereof for producing medicaments, in particular medicaments for the treatment of central nervous system diseases.