Antibodies to the cell cycle regulatory protein p16
US7425617B2 · kind B2 · utility
1Cited by
5References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 30, 1998 |
| Grant date | Sep 16, 2008 |
| Priority date | — |
| Expiry date | Nov 8, 2022 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/4739
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the discovery in eukaryotic cells, particularly mammalian cells, of a family of cell-cycle regulatory proteins (“CCR-proteins”). As described herein, this family of proteins includes a polypeptide having an apparent molecular weight of 16 kDa, and a polypeptide having an apparent molecular weight of approximately 15 kDa, each of which can function as an inhibitor of cell-cycle progression, and therefore ultimately of cell growth. The present invention comprises antibodies directed to such CCR-proteins.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.