Patent · US Expired

Site specific incorporation of keto amino acids into proteins

US7432092B2 · kind B2 · utility

14Cited by
3References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 15, 2003
Grant dateOct 7, 2008
Priority date—
Expiry dateDec 17, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P21/005
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Compositions and methods of producing components of protein biosynthetic machinery that include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, and orthogonal pairs of tRNAs/synthetases, which incorporate keto amino acids into proteins are provided. Methods for identifying these orthogonal pairs are also provided along with methods of producing proteins with keto amino acids using these orthogonal pairs.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.