HIV replication inhibiting pyrimidines and triazines

US7442705B2 · kind B2 · utility

Assignee

• Tibotec Pharmaceuticals Ltd. · IE

Inventors

• Jérôme Emile Georges Guillemont · Andé, FR
• Elisabeth Therese Jeanne Pasquier · Le Neubourg, FR
• Jan Heeres · Vosselaar, BE
• Kurt Hertogs · Antwerpen, BE
• Eva Bettens · Zoersel, BE
• Paulus Joannes Lewi · Turnhout, BE
• Marc René de Jonge · Tilburg, NL
• Lucien Maria Henricus Koymans · Retie, BE
• Frederik Frans Desiré Daeyaert · Beerse, BE
• Hendrik Maarten Vinkers · Ekeren, BE
• Jerme Emile Georges Guillemont · Val-de-Reuil, FR

Key dates

• Filing date: Feb 20, 2004
• Grant date: Oct 28, 2008
• Expiry date: Nov 9, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention concerns HIV replication inhibitors of formula (I), The N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof, their use as a medicine, their processes for preparation and pharmaceutical compositions comprising them.