Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors

US7449465B2 · kind B2 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Eddy Jean Edgard Freyne · Rumst, BE
• Christopher John Love · Deurne, BE
• Ludwig Paul Cooymans · Beerse, BE
• Nele Vandermaesen · Olmen, BE
• Peter Jacobus Johannes Antonius Buijnsters · Breda, NL
• Marc Willems · Beerse, BE
• Werner Constant Johan Embrechts · Beerse, BE

Key dates

• Filing date: Jul 12, 2004
• Grant date: Nov 11, 2008
• Expiry date: Aug 25, 2024

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention concerns compounds of formulaN-oxides, pharmaceutically acceptable addition salts, quaternary amines and stereochemically isomeric forms thereof, their use, pharmaceutical compositions comprising them, and processes for their preparation.