Anti-cancer phosphonate analogs

US7452901B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Constantine G. Boojamra · San Francisco, US
• Carina E. Cannizzaro · San Mateo, US
• James M. Chen · Bedminster, US
• Xiaowu Chen · Hillsborough, US
• Aesop Cho · Mountain View, US
• Lee S. Chong · Newark, US
• Maria Fardis · Redwood City, US
• Alan X. Huang · San Mateo, US
• Choung U. Kim · Redwood City, US
• Thorsten A. Kirschberg · Mountain View, US
• Steven Krawczyk · Palo Alto, US
• Christopher P. Lee · San Francisco, US
• Kuei-Ying Lin · Fremont, US
• Richard L. Mackman · Millbrae, US
• David Y. Markevitch · Los Angeles, US
• Peter H. Nelson · Los Altos, US
• David A. Oare · Belmont, US
• Vidya K. Prasad · Munich, DE
• Hyung-Jung Pyun · Fremont, US
• Adrian S. Ray · Redwood City, US
• Sundaramoorthi Swaminathan · Burlingame, US
• William J. Watkins · Saratoga, US
• Jennifer R. Zhang · Union City, US
• Lijun Zhang · Los Altos Hills, US

Key dates

• Filing date: Apr 26, 2004
• Grant date: Nov 18, 2008
• Expiry date: Aug 7, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H19/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is related to phosphorus substituted anti-cancer compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.