Chimeric papillomavirus-like particles

US7462356B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Douglas R. Lowy · Washington, US
• John T. Schiller · Silver Spring, US
• Heather Greenstone · Silver Spring, US

Key dates

• Filing date: May 25, 2007
• Grant date: Dec 9, 2008
• Expiry date: May 25, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2710/20023
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides a papillomavirus-like particle, characterized as having conformational epitopes, comprising a papillomavirus L1 product and a papillomavirus L2 fusion product; and related synthetic DNA molecules, host cells, methods and vaccines.