Sequence analysis of the tetravalent rotavirus vaccine

US7485415B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Deborah A. Buonagurio · Rye, US
• Alice F. Georgiu · Montgomery, US
• Robert Lerch · New Hempstead, US
• Bruce B. Mason · Linglestown, US
• Shridhara Murthy · Ann Arbor, US
• Ruth Rappaport · Strafford, US
• Mohinder S. Sidhu · New City, US
• Stephen A. Udem · New York, US
• Timothy J. Zamb · Setauket, US

Key dates

• Filing date: Feb 19, 2003
• Grant date: Feb 3, 2009
• Expiry date: May 30, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2720/12362
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated nucleic acid molecules comprising a gene segment from a rhesus rotavirus (RRV) or from one of three rhesus: human reassortant viruses are disclosed, including isolated nucleic acid molecules having a sequence selected from the group consisting of: SEQ ID NO: 1-14, inclusive, and isolated nucleic acid molecules encoding a protein having a sequence selected from the group consisting of SEQ ID NO: 15-28, inclusive, as well as variants of the isolated nucleic acid molecules.