Synthesis of indenoisoquinolines
US7495100B2 · kind B2 · utility
12Cited by
2References
10Claims
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Key dates
| Filing date | May 9, 2005 |
| Grant date | Feb 24, 2009 |
| Priority date | — |
| Expiry date | Mar 10, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D217/26
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Indenoisoquinolines and dihydroindenoisoquinolines are described. In particular, such compounds possessing one or more electron withdrawing substituents are described. The in vitro anticancer activities of these molecules tested in the National Cancer Institute's screen of 55 cell lines is described. The compounds tested for topoisomerase I (top1) inhibition is described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.