Dicarboxamide derivatives

US7501413B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Markus Boehringer
• Katrin Groebke Zbinden · Liestal, CH
• Wolfgang Haap · Bad Kötzting, DE
• Hans Hilpert · Reinach, CH
• Jacques Himber · Guebwiller, FR
• Roland Humm · Auggen, DE
• Hans Iding · Rheinfelden (Baden), DE
• Dietmar Knopp · Basel, CH
• Narendra Panday · Basel, CH
• Fabienne Ricklin · Hombourg, FR
• Christoph Martin Stahl · Glückstadt, DE

Key dates

• Filing date: Oct 31, 2005
• Grant date: Mar 10, 2009
• Expiry date: Nov 29, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention is concerned with novel dicarboxamide derivatives of formula (I)wherein A, B, Rc, D and E are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds inhibit the coagulation factor Xa and can be used as medicaments.