Mono-acylated o-phenylendiamines derivatives

US7501451B2 · kind B2 · utility

Assignee

• Hoffmann-La Roche Inc. · US

Inventors

• Georg Fertig · Penzberg, DE
• Frank Herting · Penzberg, DE
• Manfred Kubbies · Penzberg, DE
• Anja Limberg · Penzberg, DE
• Ulrike Reiff · Penzberg, DE
• Michael Weidner · Sunrise, US

Key dates

• Filing date: Dec 6, 2005
• Grant date: Mar 10, 2009
• Expiry date: Aug 30, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/02
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Mono-acylated o-phenylendiamines derivatives of formula A:which are useful for the treatment of diseases mediated by the inhibition of histone deacetylase, such as cancer.