Patent · US Expired

Phosphorus-containing thyromimetics

US7514419B2 · kind B2 · utility

15Cited by
71References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 2005
Grant dateApr 7, 2009
Priority date
Expiry dateNov 15, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F9/657181
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds of phosphonic acid-containing T3 mimetics and monoesters thereof, stereoisomers, pharmaceutically acceptable salts, co-crystals, and prodrugs thereof and pharmaceutically acceptable salts and co-crystals of the prodrugs, as well as their preparation and uses for preventing and/or treating metabolic diseases such as obesity, NASH, hypercholesterolemia and hyperlipidemia, as well as associated conditions such as atherosclerosis, coronary heart disease, impaired glucose tolerance, metabolic syndrome x and diabetes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.