Aminodicarboxylic acid derivatives having pharmaceutical properties

US7517896B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Cristina Alonso-Alija · Haan, DE
• Markus Heil · Leichlingen, DE
• Dietmar Flubacher · Glückstadt, DE
• Paul Naab · Bad Reichenhall, DE
• Josef Pernerstorfer · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Klaus Dembowsky · Boston, US
• Elizabeth Perzborn · Wuppertal, DE
• Elke Stahl · Bensberg, DE

Key dates

• Filing date: Aug 8, 2005
• Grant date: Apr 14, 2009
• Expiry date: Feb 19, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formulae (II), (IV), and (VI) as shown below,wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.