Muteins of human telomerase reverse transcriptase lacking telomerase catalytic activity
US7517971B1 · kind B1 · utility
7Cited by
68References
9Claims
0Family size
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Key dates
| Filing date | Nov 22, 2000 |
| Grant date | Apr 14, 2009 |
| Priority date | — |
| Expiry date | Nov 22, 2020 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compositions and methods related to human telomerase reverse transcriptase (hTRT), the catalytic protein subunit of human telomerase. The polynucleotides and polypeptides of the invention are useful for diagnosis, prognosis and treatment of human diseases, for changing the proliferative capacity of cells and organisms, and for identification and screening of compounds and treatments useful for treatment of diseases such as cancers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.