siRNA targeting connexin 43
US7521191B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Mar 30, 2007 |
| Grant date | Apr 21, 2009 |
| Priority date | — |
| Expiry date | Aug 6, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/11
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to connexin 43 (gap junction protein alpha 1).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.