Patent assignee · US · COMPANY

Dharmacon, Inc.

115Patents

110Active

115Granted

59Portfolio score

Filing activity: Feb 14, 2000 → Jan 7, 2014 · 99 expiring within 5 years

Most-cited patents

Patent	Title	Area	Cited by	Status
US7691997B2	Functional and hyperfunctional siRNA	Chemistry; Metallurgy	220	Active
US8090542B2	Functional and hyperfunctional siRNA	Chemistry; Metallurgy	164	Expired
US7595387B2	Modified polynucleotides for reducing off-target effects in RNA interference	Chemistry; Metallurgy	138	Expired
US7507811B2	siRNA targeting KRAS	Chemistry; Metallurgy	90	Active
US7655788B2	siRNA targeting DNA-damage-inducible transcript 4 (DDIT4)	Chemistry; Metallurgy	85	Active
US7521191B2	siRNA targeting connexin 43	Chemistry; Metallurgy	77	Active
US7511132B2	Functional and hyperfunctional siRNA directed against Bcl-2	Chemistry; Metallurgy	72	Active
US7579457B2	siRNA targeting carbonic anhydrase II	Chemistry; Metallurgy	70	Active
US7834170B2	Functional and hyperfunctional siRNA	Chemistry; Metallurgy	68	Active
US7514550B2	siRNA targeting myeloid cell leukemia sequence 1	Chemistry; Metallurgy	67	Active
US7820809B2	Functional and hyperfunctional siRNA directed against Bcl-2	Chemistry; Metallurgy	63	Expired
US7598370B2	siRNA targeting polo-like kinase-1 (PLK-1)	Chemistry; Metallurgy	63	Active
US7834171B2	Modified polynucleotides for reducing off-target effects in RNA interference	Chemistry; Metallurgy	61	Active
US6590093B1	Orthoester protecting groups	Emerging Cross-Sectional Technologies	60	Expired
US7541453B2	siRNA targeting aquaporin 4	Chemistry; Metallurgy	59	Active
US7579458B2	siRNA targeting synuclein, alpha (SNCA-1)	Chemistry; Metallurgy	58	Active
US7576196B2	siRNA targeting transducin (beta)-like 3 (TBL3)	Chemistry; Metallurgy	56	Active
US7576197B2	SiRNA targeting KRAS	Chemistry; Metallurgy	56	Active
US7598369B2	siRNA targeting histamine receptor H1	Chemistry; Metallurgy	56	Active
US7569684B2	siRNA targeting gremlin	Chemistry; Metallurgy	55	Active
US7550572B2	siRNA targeting cell division cycle 20 homolog (CDC20)	Chemistry; Metallurgy	55	Active
US7592443B2	siRNA targeting interleukin-1 receptor-associated kinase 4 (IRAK4)	Chemistry; Metallurgy	55	Active
US7632938B2	siRNA targeting superoxide dismutase 1 (SOD1)	Chemistry; Metallurgy	54	Active
US7582746B2	siRNA targeting complement component 3 (C3)	Chemistry; Metallurgy	53	Active
US7612196B2	siRNA targeting cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)	Chemistry; Metallurgy	52	Active

Source: USPTO / EPO open patent data. Counts and citation impact are objective bibliographic measures.