Comparative mycobacterial geneomics as a tool for identifying targets for the diagnosis, prophylaxis or treatment of mycobacterioses
US7538206B2 · kind B2 · utility
14Cited by
0References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Feb 22, 2002 |
| Grant date | May 26, 2009 |
| Priority date | — |
| Expiry date | Mar 13, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/505
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to a method of selection of purified nucleotidic sequences or polynucleotides encoding proteins or part of proteins carrying at least an essential function for the survival or the virulence of mycobacterium species by a comparative genomic analysis of the sequence of the genome of M. tuberculosis aligned on the genome sequence of M. leprae and M. tuberculosis and M. leprae marker polypeptides of nucleotides encoding the polypeptides, and methods for using the nucleotides and the encoded polypeptides are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.