Modulation of survivin expression
US7541344B2 · kind B2 · utility
112Cited by
14References
24Claims
0Family size
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Key dates
| Filing date | Jun 3, 2004 |
| Grant date | Jun 2, 2009 |
| Priority date | — |
| Expiry date | Sep 24, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/322
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds and compositions are provided for modulating the expression of survivin. The compounds, exemplified by those acting through an RNAi antisense mechanism of action, include double-stranded and single-stranded constructs, as well as siRNAs, canonical siRNAs, blunt-ended siRNAs and single-stranded antisense RNA compounds. Methods of using these compounds for modulation of survivin expression and for treatment of diseases associated with expression of survivin are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.