p16INK4 polypeptides
US7550561B1 · kind B1 · utility
1Cited by
1References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 14, 1994 |
| Grant date | Jun 23, 2009 |
| Priority date | — |
| Expiry date | Apr 14, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/23
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to the discovery in eukaryotic cells, particularly human cells, a novel polypeptide of 16 kDa (hereinafter “p16INK4” or “p16”) can function as an inhibitor of cell cycle progression, and therefore ultimately of cell growth, and that similar to the role of p21 and p53, the p16 protein may function coordinately with the cell cycle regulatory protein, retinoblastoma (Rb).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.