Pulsatile release compositions and methods for enhanced intestinal oligonucleotide drug absorption
US7576067B2 · kind B2 · utility
9Cited by
56References
25Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 1, 2004 |
| Grant date | Aug 18, 2009 |
| Priority date | — |
| Expiry date | Nov 1, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/4891
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Delayed release oral pharmaceutical formulations and methods for enhanced intestinal drug absorption. The formulation comprises a first population of carrier particles comprising a drug and a penetration enhancer which are released at a first location in the intestine, and a second population of carrier particles comprising a penetration enhancer and a delayed release coating or matrix. This penetration enhancer is released at a second location in the intestine downstream from the first location and enhances absorption of the drug when it reaches the second location.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.