Genetic testing kits and a method of bladder cancer
US7592137B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | May 27, 2004 |
| Grant date | Sep 22, 2009 |
| Priority date | — |
| Expiry date | Oct 19, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A deletion in the end region of the long arm of a Chromosome 9 is efficiently detected.A genetic testing kit of bladder cancer according to the present invention includes a primer allowing for efficient amplification of a region containing a site of genetic polymorphism present in the ABO blood group gene of Chromosome 9. In the site of genetic polymorphism present in the ABO blood group gene, the frequency of heterozygote (heterozygosity) in the population is extremely high. Therefore, by detecting LOH using a polymorphic site present in the ABO blood group gene, it is possible to reliably detect a deletion near the polymorphic site, in other words, a deletion near the end of the long arm of Chromosome 9.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.