siRNA targeting ribonucleotide reductase M2 polypeptide (RRM2 or RNR-R2)
US7592442B2 · kind B2 · utility
51Cited by
10References
20Claims
0Family size
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Key dates
| Filing date | Jun 13, 2007 |
| Grant date | Sep 22, 2009 |
| Priority date | — |
| Expiry date | Aug 14, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2330/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to RRM 2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.