siRNA targeting polo-like kinase-1 (PLK-1)
US7598370B2 · kind B2 · utility
63Cited by
10References
20Claims
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Key dates
| Filing date | Jun 15, 2007 |
| Grant date | Oct 6, 2009 |
| Priority date | — |
| Expiry date | Aug 6, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/11
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to PLK-1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.