Methods and compositions for increasing antibody production
US7608429B2 · kind B2 · utility
28Cited by
25References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 30, 2003 |
| Grant date | Oct 27, 2009 |
| Priority date | — |
| Expiry date | Sep 22, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides methods and compositions for improved expression and production of recombinant antibodies in host cell expression systems. In particular, prokaryotic expression and production of antibodies with modified hinge cysteine residues are provided. The invention further provides compositions, kits and articles of manufacture for practicing methods of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.