Microorganism producing 5′-xanthylic acid
US7608435B2 · kind B2 · utility
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Key dates
| Filing date | Nov 18, 2004 |
| Grant date | Oct 27, 2009 |
| Priority date | — |
| Expiry date | Sep 12, 2025 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/843
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a microorganism, obtained by treating Corynebacterium ammoniagenes KCCM 10488 producing 5′-Xanthylic acid as parent strain with UV radiation and mutation Derivatives such as N-methyl-N′nitro-N-nitrosoguanidine (NTG), Having a resistance to 5-fluorotryptophan which enhances Biosynthesis of N5-N10-tetrahydrofolate used for transferring Two formyl group during the process of puring biosynthesis, making It possible to accumulate 5′xanthylic acid in culture medium at a high Yield and high concentration rate same period of fermentation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.