Heteroaryl peptidomimetics as thrombin receptor antagonists
US7618945B2 · kind B2 · utility
0Cited by
3References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 15, 2005 |
| Grant date | Nov 17, 2009 |
| Priority date | — |
| Expiry date | Mar 5, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to novel heteroaryl peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, angiogenesis and related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted heteroaryl peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.