Heteroaryl peptidomimetics as thrombin receptor antagonists
US7629319B2 · kind B2 · utility
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17Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 10, 2003 |
| Grant date | Dec 8, 2009 |
| Priority date | — |
| Expiry date | Jun 26, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K5/06095
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention is directed to novel heteroaryl peptidomimetic compounds which are useful as thrombin receptor antagonists for the treatment of diseases associated with thrombosis, restenosis, hypertension, heart failure, arrhythmia, inflammation, angina, stroke, atherosclerosis, ischemic conditions, angiogenesis and related disorders, cancer, and neurodegenerative disorders. Pharmaceutical compositions comprising the substituted heteroaryl peptidomimetics of the present invention and methods of treating conditions mediated by the thrombin receptor are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.