Process for the preparation of 3-amino-pentan-1,5-diol
US7635784B2 · kind B2 · utility
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Key dates
| Filing date | Jun 9, 2008 |
| Grant date | Dec 22, 2009 |
| Priority date | — |
| Expiry date | Jun 9, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C271/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a novel method for preparing a key intermediate, 3-amino-pentan-1,5-diol (2), which is useful for the preparation of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)-propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidine-7-one (1) a MAP-kinase inhibitor useful in the treatment of rheumatoid arthritis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.