Therapeutic phosphonate compounds

US7645747B2 · kind B2 · utility

Assignee

• Gilead Sciences, Inc. · US

Inventors

• Constantine G. Boojamra · San Francisco, US
• Carina E. Cannizzaro · San Mateo, US
• James M. Chen · Bedminster, US
• Xiaowu Chen · Hillsborough, US
• Aesop Cho · Mountain View, US
• Lee S. Chong · Newark, US
• Manoj C. Desai · Pleasant Hill, US
• Maria Fardis · Redwood City, US
• Craig Gibbs · Palo Alto, US
• Ralph F. Hirschmann · La Cañada Flintridge, US
• Alan X. Huang · San Mateo, US
• Haolun Jin · Foster City, US
• Choung U. Kim · Redwood City, US
• Thorsten A. Kirschberg · Mountain View, US
• Steven Krawczyk · Palo Alto, US
• Christopher P. Lee · San Francisco, US
• William A. Lee · Palo Alto, US
• Kuei-Ying Lin · Fremont, US
• Richard L. Mackman · Millbrae, US
• David Y. Markevitch · Los Angeles, US
• Peter H. Nelson · Los Altos, US
• David A. Oare · Belmont, US
• Vidya K. Prasad · Munich, DE
• Hyung-Jung Pyun · Fremont, US
• Adrian S. Ray · Redwood City, US
• Rosemarie Sherlock · San Mateo, US
• Sundaramoorthi Swaminathan · Burlingame, US
• William J. Watkins · Saratoga, US
• Jennifer R. Zhang · Union City, US
• Lijun Zhang · Los Altos Hills, US

Key dates

• Filing date: Oct 25, 2005
• Grant date: Jan 12, 2010
• Expiry date: May 10, 2026

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6561
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention is related to phosphorus substituted therapeutic agents, compositions containing such phosphorus substituted agents, and therapeutic methods that include the administration of such phosphorus substituted agents, as well as to processes and intermediates useful for preparing such agents.