Ocular therapeutic agent delivery devices and methods for making and using such devices

US7658364B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Michael R. Robinson · Irvine, US
• Karl Csaky · Dallas, US
• Robert Nussenblatt · Bethesda, US
• Janine A. Smith · Potomac, US
• Peng Yuan · Houston, US
• Cynthia Sung · Silver Spring, US
• Matthew Fronheiser · Durham, US
• Hyuncheol Kim · Seoul, KR

Key dates

• Filing date: Mar 14, 2002
• Grant date: Feb 9, 2010
• Expiry date: Jul 28, 2024

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S425/808
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Ocular implant devices (10, 20, 121) for the delivery of a therapeutic agent to an eye (101, 301) in a controlled and sustained manner. Dual mode and single mode drug delivery devices (10, 20, 121) are illustrated and described. Implants (10, 20) suitable for subconjunctival placement are described. Implants (121, 10, 20) suitable for intravitreal placement also are described. The invention also includes fabrication and implementation techniques associated with the unique ocular implant devices (10, 20, 121) that are presented herein.