Naphthylene derivatives as cytochrome P450 inhibitors
US7662844B2 · kind B2 · utility
5Cited by
4References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 12, 2004 |
| Grant date | Feb 16, 2010 |
| Priority date | — |
| Expiry date | Jul 12, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D233/64
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formulaand pharmaceutically acceptable salts thereof, wherein n1, n2, n3, n4, G1, Q1, Z, R1, R2, R3, R4a, R4b, R5a, and R5b are defined herein, inhibit the cytochrome P450RAI enzyme and are useful for the treatment and/or prevention of various diseases and conditions which respond to treatment by retinoids and by naturally occurring retinoic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.