Cloned genome of infectious hepatitis C virus strain HC-TN and uses thereof

US7678569B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Jens Bukh · Bethesda, US
• Robert H. Purcell · Boyds, US
• Suzanne U. Emerson · Rockville, US
• Akito Sakai · Kawasaki, JP

Key dates

• Filing date: Apr 2, 2008
• Grant date: Mar 16, 2010
• Expiry date: Apr 2, 2028

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2500/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Embodiments described herein include nucleic acid sequences, which encode hepatitis C virus of strain HC-TN, genotype 1a, proteins and polypeptides and fragments thereof. Use of these compositions, and diagnostics for HCV and in the development of screening assays for the identification of antiviral agents for HCV are also contemplated.