Patent · US Active

Method for predicting the response to a treatment

US7700299B2 · kind B2 · utility

30Cited by

1References

11Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Joachim Moecks · Mannheim, DE
Andreas Strauss · Forchheim, DE
Gerhard Zugmaier · Munich, DE

Key dates

Filing date	May 19, 2006
Grant date	Apr 20, 2010
Priority date	—
Expiry date	Nov 17, 2027

Classification

Technology area (CPC G)Physics
CPC primaryG01N2800/52
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention is related to a method of predicting the response to a treatment with a HER inhibitor in a patient comprising the steps of assessing a biomarker or a combination of biomarkers selected from the group consisting of amphiregulin, an epidermal growth factor, a transforming growth factor alpha, and a HER2 biomarker in a biological sample from the patient and predicting the response to the treatment with the HER inhibitor in the patient by evaluating the results of the first step. Further uses and methods wherein these markers are used are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.