Biosensors, method for obtaining the same and uses thereof
US7700303B2 · kind B2 · utility
0Cited by
4References
16Claims
0Family size
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Key dates
| Filing date | Aug 16, 2007 |
| Grant date | Apr 20, 2010 |
| Priority date | — |
| Expiry date | Mar 20, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/566
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention relates to biosensors, methods for obtaining them and their use for detecting, assaying or locating, in direct immunofluorescence, a ligand such as an antigen or hapten, in a heterogeneous population. The biosensor includes (i) at least one fragment of a receptor which is protein in nature, capable of binding to a ligand via an active site, where at least one amino acid residues of the fragment located in the proximity of the active site is naturally present in the form of a cystein (Cys) residue, or is substituted with a Cys residue, and (ii) a fluorophore coupled to the Cys residue.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.