Patent · US Active

Crystalline forms of a biphenyl compound

US7700777B2 · kind B2 · utility

36Cited by
2References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 8, 2007
Grant dateApr 20, 2010
Priority date
Expiry dateAug 8, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.