ErbB4 antagonists
US7704498B2 · kind B2 · utility
15Cited by
12References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 2008 |
| Grant date | Apr 27, 2010 |
| Priority date | — |
| Expiry date | Jun 24, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention concerns methods and means for controlling excessive proliferation and/or migration of smooth muscle cells, and in particular for treating stenosis, by using antagonists of a native ErbB4 receptor. The invention further concerns a method for the identification of ErbB4 agonists and antagonists capable of inhibiting or enhancing the proliferation or migration of smooth muscle cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.