Oligomers comprising activated disulfides which bind to plasma proteins and their use for delivery to cells
US7713944B2 · kind B2 · utility
37Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 13, 2005 |
| Grant date | May 11, 2010 |
| Priority date | — |
| Expiry date | Oct 13, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/549
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The activated oligomer compounds described herein are capable of forming bio-reversible covalent bonds with plasma proteins, in particular with human serum albumin. The plasma protein-oligomer complexes of the present invention exhibit enhanced cellular entry and significantly enhanced serum half-life.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.