Polypeptides for inducing a protective immune response against Staphylococcus aureus
US7718182B2 · kind B2 · utility
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2References
13Claims
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Key dates
| Filing date | Jan 17, 2006 |
| Grant date | May 18, 2010 |
| Priority date | — |
| Expiry date | Jan 17, 2026 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention features polypeptides comprising an amino acid sequence structurally related to SEQ ID NO: 1 or a fragment thereof, S. aureus AhpC-AhpF compositions, and uses of such polypeptides and compositions. SEQ ID NO: 1 has a full length S. aureus AhpC sequence. A derivative of SEQ ID NO: 1 containing an amino His-tag and three additional carboxyl amino acids was found to produce a protective immune response against S. aureus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.