Patent · US Active

Thiophene derivatives which are HM74A agonists

US7732452B2 · kind B2 · utility

1Cited by

1References

26Claims

0Family size

Assignee

Hoffmann-La Roche Inc. · US

Inventors

Henrietta Dehmlow · Weil am Rhein, DE
Uwe Grether · Weil am Rhein, DE
Nicole A. Kratochwil · Sool, CH
Robert Narquizian · La Valette-du-Var, FR
Constantinos G. Panousis · Bottmingen, CH

Key dates

Filing date	Dec 13, 2006
Grant date	Jun 8, 2010
Priority date	—
Expiry date	Dec 13, 2026

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D333/38
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is concerned with novel substituted thiophene derivatives of formula (I)wherein R1 to R8, X, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.