7-amino alkylidenyl-heterocyclic quinolones and naphthyridones

US7732612B2 · kind B2 · utility

Assignee

• Janssen Pharmaceutica NA · BE

Inventors

• Eugene B. Grant · Flemington, US
• Mark J. Macielag · Spring House, US
• Steven Paget · Dover, US
• Michele A. Weidner-Wells · Fryeburg, US
• Xiaoqing Xu · Monmouth Junction, US
• Xiaodong Xu · Bound Brook, US

Key dates

• Filing date: Mar 21, 2005
• Grant date: Jun 8, 2010
• Expiry date: Jul 2, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds having a structure according to Formula Iwherein n, m, z, R, R2, R3, R4, R5, R6, A, E, X, Y, a and b are as defined above;or an optical isomer, diastereomer or enantiomer thereof; a pharmaceutically acceptable salt, hydrate, or prodrug thereof.