Patent · US Expired

Histone deacetylase inhibitors

US7737184B2 · kind B2 · utility

1Cited by
6References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 8, 2005
Grant dateJun 15, 2010
Priority date
Expiry dateMay 3, 2026

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C2603/18
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to hydroxamic acid derivatives having a urea linkage, that are inhibitors of histone deacetylase (HDAC), and are useful in the prevention and/or treatment of cellular proliferative diseases, for example cancer, autoimmune, allergic and inflammatory diseases, diseases of the central nervous system (CNS) such as neurodegenerative diseases, and in the prevention and/or treatment of restenosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.