Quinazolinone T-type calcium channel antagonists
US7745452B2 · kind B2 · utility
4Cited by
0References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 8, 2006 |
| Grant date | Jun 29, 2010 |
| Priority date | — |
| Expiry date | Apr 10, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D405/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to quinazolinone compounds of the formula I:wherein R1, R2, R3, X1, X2 X3 are defined herein. These compounds are antagonists of T-type calcium channels, and are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.