Optimized sample injection structures in microfluidic separations
US7749365B2 · kind B2 · utility
34Cited by
88References
20Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 26, 2006 |
| Grant date | Jul 6, 2010 |
| Priority date | — |
| Expiry date | Apr 20, 2029 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/2575
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention herein provides improved sample injection systems and related methods to create microfluidic devices with symmetrical channel configurations that can produce relatively large sample volumes. An embodiment of the invention provides microfluidic structures with different geometries that are symmetrical from the perspective of a sample load channel and a sample waste channel, which essentially eliminates issues of time offset and other problems commonly associated with twin-T sample formation techniques. A split-injection approach and related methods of sample plug formation are therefore provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.