Method of preventing infections from bioterrorism agents with immunostimulatory CpG oligonucleotides

US7758876B2 · kind B2 · utility

Assignee

• The United States of America, as represented by the Department of Health and Human Services · US

Inventors

• Dennis Klinman · Potomac, US
• Bruce Ivins · Frederick, US
• Daniela Verthelyi · Potomac, US

Key dates

• Filing date: Oct 31, 2003
• Grant date: Jul 20, 2010
• Expiry date: Jul 9, 2025

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure relates to a method of preventing or treating an infection caused by a bioterrorism agent, specifically to a method of increasing an immune response to a bioterrorism agent using an oligodeoxynucleotide including a CpG motif, and a method of enhancing the immunogenicity of a vaccine against a bioterrorism agent using an oligodeoxynucleotide including a CpG motif.