Indol-3-y-carbonyl-piperidin and piperazin-derivatives
US7781436B2 · kind B2 · utility
18Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 25, 2006 |
| Grant date | Aug 24, 2010 |
| Priority date | — |
| Expiry date | Aug 21, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to indol-3-yl-carbonyl-piperidin and piperazin derivatives which act as V1a receptor antagonists and which are represented by Formula I:wherein the residues R1 to R3 are as defined herein. The invention also relates to pharmaceutical compositions containing such compounds, and methods for preparation of the compounds and compositions. The invention further relates to methods for treating dysmenorrhea, hypertension, chronic heart failure, inappropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, obsessive compulsive disorder, anxiety and depressive disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.