Aminodicarboxylic acid derivatives having pharmaceutical properties

US7781470B2 · kind B2 · utility

Assignee

• Bayer Schering Pharma AG · DE

Inventors

• Cristina Alonso-Alija · Haan, DE
• Markus Heil · Leichlingen, DE
• Dietmar Flubacher · Glückstadt, DE
• Paul Naab · Bad Reichenhall, DE
• Josef Pernerstorfer · Wuppertal, DE
• Johannes-Peter Stasch · Wuppertal, DE
• Frank Wunder · Wuppertal, DE
• Klaus Dembowsky · Boston, US
• Elizabeth Perzborn · Wuppertal, DE
• Elke Stahl · Bensberg, DE

Key dates

• Filing date: Apr 13, 2009
• Grant date: Aug 24, 2010
• Expiry date: Apr 13, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/10
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to compounds of formulae (II), (IV), and (VI) as shown below,wherein the several variable groups are as defined in the specification and claims. Processes for making these materials, and methods for using them in the synthesis of compounds for treatment of cardiovascular disorders and fibrotic disorders are also disclosed.