Anti-neurturin receptor-A antibody compositions comprising cytokines or neurotrophic factors
US7785588B2 · kind B2 · utility
15Cited by
3References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 22, 2006 |
| Grant date | Aug 31, 2010 |
| Priority date | — |
| Expiry date | Aug 22, 2026 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
NTNRα, NTNRα extracellular domain (ECD), NTNRα variants, chimeric NTNRα (e.g., NTNRα immunoadhesion), and antibodies which bind thereto (including agonist and neutralizing antibodies) are disclosed. Various uses for these molecules are described, including methods to modulate cell activity and survival by response to NTNRα-ligands, for example NTN, by providing NTNRα to the cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.