Patent · US Active

Substituted benzimidazole derivatives

US7790904B2 · kind B2 · utility

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0References

31Claims

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Assignee

Hoffmann-La Roche Inc. · US

Inventors

Gregory Martin Benson · Therwil, CH
Konrad Bleicher · Glückstadt, DE
Uwe Grether · Weil am Rhein, DE
Rainer E. Martin · Basel, CH
Jean-Marc Plancher · Rixheim, FR
Hans Richter · Weil am Rhein, DE
Sven Taylor · Riedisheim, FR
Minmin Yang · Nanjing, CN

Key dates

Filing date	Aug 22, 2008
Grant date	Sep 7, 2010
Priority date	—
Expiry date	Aug 22, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D405/12
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention is concerned with novel substituted benzimidazole derivatives of formula (I)wherein R1 to R10 and X are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds bind to FXR and can be used as medicaments.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.