Patent · US Expired

Process for producing array plate for biomolecules having hydrophilic and hydrophobic regions

US7794799B1 · kind B1 · utility

37Cited by
11References
40Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 15, 2003
Grant dateSep 14, 2010
Priority date
Expiry dateDec 14, 2025

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC40B60/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A method for manufacturing an array plate for biomolecules includes coating a surface of a substrate with a hydrophobic material to form a hydrophobic layer having initial hydrophobic properties, etching the hydrophobic layer through an etch mask placed thereon to form a hydrophilic binding site, removing the etch mask, and processing the remaining region of the hydrophobic layer to recover the initial hydrophobic properties. A method for manufacturing a biochip using this array plate, includes processing the surface of the hydrophilic binding site of the array plate to increase an affinity of biomolecules to the hydrophilic binding site, and applying a solution containing biomolecules to the surface of the hydrophilic binding site.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.